Lgals3-Transitioned Inflammatory Smooth Muscle Cells: Major Regulators of Atherosclerosis Progression and Inflammatory Cell Recruitment
Arteriosclerosis, Thrombosis, and Vascular Biology · 07 Jul 2022
Heterogeneous subpopulations of adventitial progenitor cells regulate vascular homeostasis and pathological vascular remodeling.
Cardiovascular research · 14 May 2021
High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling.
Arteriosclerosis, thrombosis, and vascular biology · 25 Jun 2020
PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Arteriosclerosis, thrombosis, and vascular biology · 19 Dec 2019
JCI insight · 22 Feb 2018
Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4.
Circulation research · 09 Nov 2016
Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation.
Nature communications · 04 Mar 2016
Vascular smooth muscle cell-derived transforming growth factor-β promotes maturation of activated, neointima lesion-like macrophages.
Arteriosclerosis, thrombosis, and vascular biology · 13 Feb 2014
Selective inactivation of PTEN in smooth muscle cells synergizes with hypoxia to induce severe pulmonary hypertension.
Journal of the American Heart Association · 31 May 2013
Serum response factor regulates expression of phosphatase and tensin homolog through a microRNA network in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology · 22 Sep 2011
SDF-1α induction in mature smooth muscle cells by inactivation of PTEN is a critical mediator of exacerbated injury-induced neointima formation.
Arteriosclerosis, thrombosis, and vascular biology · 17 Mar 2011
Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation.
Cardiovascular research · 05 Jan 2010